The drug to fight fine wrinkles and dermal creases based on a combination of two powerful peptides: Acetyl Hexapeptide-8 (Argireline, a botox-like peptide), and Pentapeptide-18, an effective muscle relaxant peptide that is a safe alternative to Botox injections.
Acetyl Hexapeptide-8 is a unique anti-wrinkle peptide produced using innovative technology from South Korean manufacturers with proven effectiveness against the formation of skin folds. Unlike a neuroprotein, its action is not paralyzing; when it is used, natural facial expressions are preserved, although the facial muscles relax.
Pentapeptide-18 is a polypeptide consisting of 5 amino acids: alanine, glycine, leucitine, phenylalanine, tyrosine. It reduces the depth of wrinkles on the face, especially in the eye area and on the forehead by increasing the production of collagen.
Due to the ability of sodium hyaluronate, which is part ofthe preparation, to saturate cells with moisture and retain it inside, as well as optimally moisturize the dermis and activate fibroblasts, Argireline blocks skin aging, is able to smooth fine wrinkles and nourish the skin with useful substances throughout the depth, as well as protect from the negative impact of external factors.
It’s ready to use serum, no need to mix. And no need to transport in cold container.
This cosmetic active ingredient, called Argireline, is a part of the peptide family that smoothes out expression lines and plumps up the skin without having to resort to aesthetic medicine and in particular to botulinum toxin injections.
Argireline (acetyl-hexapeptide-3) is a unique peptide, a chain of six amino acids that reduces the appearance of existing facial wrinkles, as has been effectively demonstrated during its development phase. This solution is a non-toxic, safer and gentler alternative to botulinum toxin , targeting the same wrinkle formation mechanism but in a very different way.
Muscles contract when they receive neurotransmitters released from a nerve cell and botulinum toxin type A paralyzes the muscle by selectively blocking the release of acetylcholine at the neuromuscular junction. Botulinum toxin irreversibly fragments the SNAP-25 protein, preventing the formation of the SNARE complex. The nerve signal cannot be transmitted, so the muscle cannot contract. Argireline is analogous to the N-terminus of SNAP-25 and competes with the natural protein for a position in the SNARE complex, destabilizing its formation without breaking any of its components.
If the SNARE complex Leuphasyl is a pentapeptide that mimics the natural pathway of enkephalins, acting on the formation of expression lines in a new way, is slightly destabilized, the vesicle cannot release neurotransmitters. It is a modified enkephalin that couples to the enkephalin receptor on the outside of the nerve cells.
What are the side effects of Argireline injection?
While not everyone experiences adverse effects from Argireline, if you have sensitive skin, you may feel stinging, redness, and dry, flaky skin at contact places. The makers also recommend when applying peptide-containing products to burnt or sensitive skin, use caution.
Does Argireline paralyze muscles?
Chemical structure of Argireline
Argireline is a peptide that affects the communication between the nerve and the muscle, so that the muscles cannot contract properly. In addition to its paralyzing effects on the muscles, it also stimulates collagen production, which helps to keep the skin smooth and wrinkle-free.
Does Argireline freeze your face?
Argireline. This peptide has made waves on social media for being “Botulinum toxin in a bottle.” Hyperbolic? Maybe. But there is some research that shows it really can act similarly to the injectable botulinum toxin — which freezes facial muscles, thus smoothing expression lines — when applied topically.
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